The prognostic effect of cardiac rehabilitation in the era of acute revascularisation and statin therapy: A systematic review and meta-analysis of randomized and non-randomized studies – The Cardiac Rehabilitation Outcome Study (CROS).
This study by Rauch et al (Eur J Prev Card- Dec 2016) examined the effect of multi-component cardiac rehabilitation on total mortality and other clinical endpoints in the modern era of statins and acute revascularisation. The authors performed a systematic review and meta-analysis to pool together the results of 25 studies including 219,702 patients after acute coronary syndrome, CABG, or with a mixed cardiac disease diagnosis from the year 1995 onward.
The results showed significantly reduced mortality for CR participants after ACS and CABG. This highlights the importance of the CR intervention, even in the modern treatment era. However, the variation in study designs and content of CR programs demonstrated a need for defining international standards for CR program delivery and scientific evaluation.